Covalence is a chemistry-themed cooperative card game where players work together to accurately build a number of secret organic molecules. One player has knowledge of a set of Secret Molecules. All other players must deduce what these secret molecules are, based upon clues given to them. Players must cooperatively construct their molecules before the clues run out!

How To Play Covalence: A Molecule Building Game

One player takes on the role of the “Knower” while all other players then become the “Builders”. The Knower has access to a number of Secret Molecules and will give the Builders clues about these as they attempt to identify their structure. After setting up the Clue cards in front of her, the Knower will randomly designate 3 Secret Molecule cards for each Builder (4 Secret Molecules if there is only one Builder). Each Builder then takes a set of Element Tiles that bear a variety of elements and bonding patterns.

The Knower must study the Secret Molecules designated to each Builder and then give each Builder clue cards that relate to their specific Molecule!

Each Builder must interpret these Clues as they arrange and rearrange their individual Element Tiles, attempting to deduce the structure of their Secret Molecule.

Builders may request new Clues from the Knower as the game progresses with their limited supply of Clue Tokens.

When the Builders think that the molecular structures they have built match their Secret Molecules, they submit their structure to the Knower with a Guess Token.

If the Builders submit their molecular structures and are wrong, they have exhausted precious resources and are that much closer to losing the game.

If the Builders submit their molecular structures and are correct, they receive more Clue Tokens as a reward and may begin building their next Secret Molecule! If each Builder is able to correctly build all of their Secret Molecules, everyone wins!

Covalence: A Molecule Building Game - What's in the Box

• 52 Molecule Cards
• 45 Element Tiles
• 18 Organic Clue Cards
• 11 Number Clue Cards
• 8 Clue Tokens
• 7 Guess Tokens